Veterinary Injectable Phenylbutazone 20% Dexamethasone Injection for Horses, 100ml
Composition (Each ml contains):
• Phenylbutazone: 200mg
• Dexamethasone (as sodium phosphate): 0.38 mg
• Excipient: Q.S.P. 100 ml
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Mechanism of Action:
Dexamethasone is a member of the glucocorticoid family, providing potent immunosuppressive and anti-inflammatory actions. It inhibits lytic enzymes released during inflammation and stress, decreasing macrophage phagocytosis.
Phenylbutazone belongs to the NSAIDs group. It inhibits prostaglandin effects that cause pain, fever, and inflammation. It reduces vascular permeability in early stages, preventing edema and diapedesis. The combination of these two ingredients ensures predominant pain relief and anti-inflammatory effects.
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Indications of Use:
Used as an anti-inflammatory, antipyretic, and analgesic agent. Specifically indicated for musculoskeletal inflammations such as arthritis, osteoarthritis, laminitis, and tendonitis in horses.
🟦 Dosage and Administration
| Horses |
20 ml/day by slow IV injection; can be repeated depending on severity. |
| Foals |
Slow IV or deep IM: 6 - 10 ml, repeated 24 - 48 hours later depending on severity. |
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Contraindications:
Contraindicated in animals with heart, liver, or kidney problems, or in the end term of pregnancy. In cases of vascular brittle and congestion, the dose must be decreased and the second dose avoided.
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Precautions & Storage:
• Withdrawal Time: None.
• Shelf Life: Use within 28 days after the first dose.
• Storage: Protect from direct sunlight; store at 15 - 25° C.
• Do not use concomitantly with other NSAIDs or corticosteroids.
• IV injection must be performed slowly. Keep out of reach of children.
🟦 Frequently Asked Questions
Q1: What are the main active ingredients in this injection?
The injection contains Phenylbutazone (200mg/ml) and Dexamethasone (0.38mg/ml), combining an NSAID with a glucocorticoid for enhanced anti-inflammatory effects.
Q2: Which conditions is this product specifically used for in horses?
It is primarily used for musculoskeletal inflammations, including arthritis, osteoarthritis, laminitis, and tendonitis.
Q3: How should the dosage be administered to foals?
For foals, the recommended dosage is 6-10 ml via slow IV or deep IM injection, which can be repeated after 24-48 hours depending on the case severity.
Q4: Are there any specific storage requirements?
Yes, the product should be stored between 15 - 25° C and protected from direct sunlight. Once opened, the remaining medicine should be used within 28 days.
Q5: Is there a withdrawal period for this medication?
According to the product specifications provided, there is no withdrawal time required.
Q6: Can this be used with other anti-inflammatory drugs?
No, it should not be used concomitantly with other NSAIDs or corticosteroid drugs to avoid potential adverse effects.
Seaoriva Medical
