💡 Mechanism of Action:
Dexa is a member of the glucocorticoid family, providing immunosuppressive and anti-inflammatory actions by inhibiting lytic enzymes released during inflammation and stress. It also decreases macrophage phagocytosis.
Phenylbutazone, an NSAID, inhibits prostaglandins that cause pain, fever, and inflammation. It works in the early stages of inflammation to reduce vascular permeability, preventing edema and diapedesis.
The combination of these two active ingredients ensures predominant anti-inflammatory and pain relief effects.
🐎 Indications of Use:
Indicated for anti-inflammatory, antipyretic, and analgesic purposes. Effective for musculoskeletal inflammations such as arthritis, osteoarthritis, laminitis, and tendonitis in horses.
⚠️ Contraindications & Precautions:
- Contraindicated for animals with heart, liver, or kidney problems.
- Do not use in the end term of pregnancy.
- In cases of vascular brittle or congestion, decrease the dose and do not apply a second dose.
- Do not use concomitantly with other NSAIDs or corticosteroid drugs.
- Slow IV injection is mandatory.
- Keep out of reach of children and do not exceed recommended dosage.
Storage: Protect in 15 - 25°C, away from direct sunlight. Once opened, the remaining medicine must be used within 28 days.
Withdrawal Time: None.
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Frequently Asked Questions
Q1: What are the main indications for Phenylbutazone Injection?
It is primarily used as an anti-inflammatory, antipyretic, and analgesic for musculoskeletal conditions in horses, such as arthritis, laminitis, and tendonitis.
Q2: Can this product be administered to foals?
Yes, foals can receive 6-10 ml via slow IV or deep IM injection, with a repeat dose possible after 24-48 hours depending on severity.
Q3: How should Phenylbutazone Injection be stored?
It should be stored between 15 - 25°C, protected from direct sunlight. Once the vial is opened, it must be used within 28 days.
Q4: Are there any specific administration precautions?
IV injections must be performed slowly. Do not use it alongside other NSAIDs or corticosteroids, and avoid use in animals with heart, liver, or kidney dysfunction.
Q5: Is there a withdrawal period for this medication?
According to the provided specifications, there is no withdrawal time required for this specific formulation.
Q6: What is the mechanism of the combination formula?
It combines Phenylbutazone (NSAID) and Dexa (Glucocorticoid). Phenylbutazone blocks prostaglandins to reduce pain/fever, while Dexa provides powerful immune suppression and anti-inflammatory action at the cellular level.