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Product Description
Veterinary Injectable Phenylbutazone 20% Dexa Injection for Horses
Composition (Each ml contains):
• Phenylbutazone: 200mg
• Dexa (as sodium phosphate): 0.38 mg
• Excipient: Q.S.P. 100 ml
Mechanism of Action
Dexa: A member of the glucocorticoid family, it exerts immunosuppressive and anti-inflammatory actions. It inhibits lytic enzymes released during inflammation and severe stress, and decreases phagocytosis by macrophages.
Phenylbutazone: An NSAID that inhibits prostaglandin production to block pain, inflammation, and fever. It reduces vascular permeability in early-stage inflammation, preventing edema and diapedesis.
The combination provides synergistic anti-inflammatory and predominant pain relief.
Indications of Use
Used as an anti-inflammatory, antipyretic, and analgesic. Specifically for musculoskeletal inflammations such as arthritis, osteoarthritis, laminitis, and tendonitis in horses.
Dosage and Administration
| Animal Type |
Dosage Protocol |
| Horses |
20 ml/day by slow IV injection; repeat based on severity. |
| Foals |
Slow IV or deep IM: 6 - 10 ml; repeat after 24 - 48 hours depending on severity. |
Safety & Precautions
- Contraindications: Do not use in animals with heart, liver, or kidney problems, or during late-term pregnancy.
- Withdrawal Time: None.
- Stability: Once opened, the medicine can be used for 28 days.
- Storage: Protect from direct sunlight; store at 15 - 25° C.
- Warning: Must be administered slowly for IV injection. Do not exceed recommended dosage.
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Frequently Asked Questions
What is Phenylbutazone 20% Dexa Injection used for?
It is primarily used in horses as an anti-inflammatory, antipyretic, and analgesic treatment for musculoskeletal conditions like arthritis, laminitis, and tendonitis.
How should this product be administered to foals?
For foals, it can be administered via slow IV or deep IM injection at a dosage of 6-10 ml, which can be repeated after 24-48 hours.
Are there any specific storage requirements?
Yes, the product should be kept in its box, protected from direct sunlight, and stored at temperatures between 15°C and 25°C.
Can this be used for horses with kidney or liver issues?
No, this product is contraindicated for animals with known heart, liver, or kidney problems, as well as those in the end term of pregnancy.
How long can I use the vial after the first dose?
The remaining medicine in the vial can be used for up to 28 days after the initial opening.
Can it be used alongside other NSAIDs?
No, it should not be used concomitantly with other NSAIDs or corticosteroid drugs.